Direct Proof Of Use
The clearest public record of HIMARS use in the 2001 War in Afghanistan is the May 24, 2018 strike in Musa Qala, Helmand Province. In a May 30 Defense Department briefing, General John W. Nicholson said Marines tracked Taliban leaders who had returned from the Farah fighting to a meeting in Musa Qala and struck them with HIMARS rockets.
DVIDS published U.S. Forces Afghanistan video metadata for the same date and location, describing an M142 HIMARS strike on a high-level Taliban command-and-control node. Voice of America separately reported that the U.S. military confirmed a ground-based rocket-artillery strike with the M142 HIMARS against a gathering of Taliban leaders in Musa Qala.
Sources: DOD Nicholson Afghanistan Briefing, DVIDS HIMARS Strike Video, VOA Afghanistan HIMARS Strike
Operational Context
Nicholson placed the strike after the Taliban's May 2018 attack on Farah city. He said Taliban fighters from Helmand joined local fighters in Farah, Afghan forces drove them out within about a day with U.S. support, and some of the leaders and fighters then returned to Helmand.
In response to Associated Press questioning at the same briefing, Nicholson said the meeting included the Taliban deputy shadow governor of Helmand and other commanders, and he characterized the target set as part of the Helmand network tied to Abdul Manan. The reported HIMARS use therefore appears in the public record as a coalition precision-fire strike against Taliban command personnel rather than as a broad area-fire mission.
Sources: DOD Nicholson Afghanistan Briefing, Military Times AP HIMARS Report
Reported Effects
Nicholson said the strike killed dozens of enemy leaders, while Voice of America and Associated Press reporting cited U.S. military confirmation that at least 50 Taliban leaders were killed. The casualty figures are therefore best treated as U.S.-attributed assessments rather than independently verified counts.
The strike fits the catalog's compact role for HIMARS in Afghanistan: U.S.-led forces used the truck-mounted rocket system for rocket strike support and long-range precision fire against a command node during the post-2015 Operation Freedom's Sentinel phase of the war.
Sources: DOD Nicholson Afghanistan Briefing, VOA Afghanistan HIMARS Strike, Military Times AP HIMARS Report