Direct proof of use
The PzH 2000 is directly documented in the 2001 War in Afghanistan through Dutch, German, manufacturer, and imagery sources. Dutch Defence Press reported that Dutch PzH-2000NL 155 mm self-propelled howitzers made their combat debut during Operation Medusa in September 2006, where two Dutch systems supported Canadian and coalition forces in Kandahar.
A KNDS PzH 2000 brochure also states that both the Royal Netherlands Army and the German Bundeswehr deployed PzH 2000s in Afghanistan to reinforce and support troops, and identifies Operation Medusa as a combat assignment in which the system provided indirect fire support for ISAF forces.
Sources: Dutch Defence Press Operation Medusa report, KNDS PzH 2000 brochure
Dutch fire support in Uruzgan and Chora
The Dutch record places PzH 2000NL howitzers in the NATO-led mission as fire-support assets for Task Force Uruzgan. Dutch Defence Press said three Dutch systems were deployed to Afghanistan, with howitzers intended for Kamp Holland at Tarin Kowt, Deh Rawod, and reserve coverage between those bases.
The Netherlands' Landmacht magazine later summarized the Royal Netherlands Army artillery contribution in Uruzgan, saying the armored howitzers stood at Tarin Kowt and Deh Rawod and that ISAF operations often depended on the availability of these heavy guns. A Wikimedia Commons image further documents a Dutch PzH 2000 firing on Taliban positions in Chora on 2007-06-16.
Sources: Dutch Defence Press Operation Medusa report, Landmacht Uruzgan Artillery Standard, Dutch PzH 2000 Chora image
German employment near Kunduz
German sources document later Bundeswehr PzH 2000 use in northern Afghanistan. A Bundeswehr retrospective on the Good Friday Battle says a PzH 2000 fired from Camp Kunduz after ground troops requested support to stop Taliban fighters from seizing an abandoned vehicle, and identifies the action as the first combat use of artillery in Bundeswehr history.
A separate Bundeswehr equipment overview says PzH 2000s stationed at several German bases in Afghanistan could fire around their bases, using smoke rounds to cover friendly movement and high-explosive rounds to destroy enemy positions. The sourced record supports NATO coalition fire support by Dutch and German forces; it does not support Taliban use or Afghan government ownership of the PzH 2000.
Sources: Bundeswehr Good Friday Battle, Bundeswehr Heavy Equipment in Afghanistan