Direct proof of use
The documented Afghanistan use for this cartridge family centers on the U.S. Army's M855A1 Enhanced Performance Round, a 5.56 mm service load introduced during the war. On June 23, 2010, the Army announced that it had begun shipping M855A1 to support warfighters in Afghanistan and said soldiers there would begin using the new round that summer.
Later Army releases described the round as fielded to soldiers in Afghanistan, replacing the M855 cartridge used by U.S. troops since the early 1980s. A 2012 Army article stated that M855A1 was performing under combat conditions in Afghanistan and had initially been fielded to troops there in July 2010 for training and combat operations.
Sources: Army Begins Shipping M855A1, Army M855A1 Fielding Demonstration, Army M855A1 Combat Conditions
Timeline
The public fielding sequence begins in June 2010, when the Army announced shipments of the M855A1 5.56 mm cartridge for Afghanistan. In April 2011, Program Executive Office Ammunition described the prior June fielding to soldiers in Afghanistan and the replacement of M855 in U.S. service.
By late 2011, Army reporting on Picatinny Arsenal's award-winning inventions said that about 30 million M855A1 Enhanced Performance Rounds had been fielded in Afghanistan since June. In August 2012, the Army described the round as performing under combat conditions in Afghanistan and identified July 2010 as its initial fielding to troops there.
Sources: Army Begins Shipping M855A1, Army M855A1 Fielding Demonstration, Picatinny Greatest Inventions, Army M855A1 Combat Conditions
Narrative
In Afghanistan, the 5.56x45 mm cartridge record is not a generic claim that every NATO 5.56 mm load was used by every coalition force. The direct sources identify a specific U.S. Army load, M855A1, and tie it to U.S. troops in Afghanistan during the later Operation Enduring Freedom period.
The Army described M855A1 as tailored for the M4 weapon system while also improving performance in the M16 and M249 weapon families. That makes the cartridge relevant to U.S. infantry small arms in Afghanistan, but the cited record supports the cartridge and service-load fielding rather than a specific firefight, unit-by-unit ammunition expenditure, or Taliban use.
The conflict-side attribution is therefore limited to United States, NATO, and Afghan government forces, with the direct evidence specifically naming U.S. soldiers in Afghanistan. The sources support shipment, fielding, replacement of M855, and reported combat-condition use of the M855A1 in the Afghanistan theater.
Sources: Army Begins Shipping M855A1, Army M855A1 Fielding Demonstration, Army Green Bullet Switch, Army M855A1 Combat Conditions